Falls in Synucleinopathies
نویسندگان
چکیده
منابع مشابه
ExPLAining early synucleinopathies
This scientific commentary refers to 'Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson's disease brain', by Roberts et al. (doi: 10.1093/brain/awv040). Parkinson's disease is the commonest movement disorder, with an estimated lifetime risk of 1.5% (de Rijk et al., 1995). It is characterized by severe cell loss in the substantia nigra and neu...
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Synucleinopathies are characterized by the presence of different types of alpha-synuclein (AS)-positive inclusion in the brain. Thus, whereas Lewy bodies are the hallmark of Parkinson disease and dementia with Lewy bodies, glial and neuronal cytoplasmic inclusions are shown by multiple system atrophy. Because the main component of all these inclusions is conformationally modified AS, aggregatio...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 2019
ISSN: 0317-1671,2057-0155
DOI: 10.1017/cjn.2019.287